Cryoimmunotherapy: superficial basal cell cancer and squamous cell carcinoma in situ treated with liquid nitrogen followed by imiquimod.

tients showed inflammatory lesions that waned after MEL treatment (P .003), and 5 patients had hyperkeratotic lesions that subsequently disappeared (P .02). Three of 13 patients’ areas of disease showed decreased infiltration during the study. Six patients reported scalp pain before or during the study, but none by the end (P .008). While 10 of 13 patients reported itching at baseline or during the study, none indicated pruritus by the end of the study (P .001). An increased growth of hair after 4 to 8 weeks was observed in 3 patients, with stable remission in 2. In 1 patient with canities, repigmentation of hair appeared.